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MINCHIN LAB

ADIPOSE TISSUE BIOLOGY & DISEASE

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Selected publications

(* = joint first author; ^ = corresponding author)

  • Adaptation of blind cavefish to nutrient poor environments: uncovering diverse new mechanisms that regulate body fat levels. Minchin JEN^. Developmental Biology. 2019 In Press.

  • Human Semaphorin 3 variants link development of melanocortin circuits and energy homeostasis. Agatha A. van der Klaauw*, Sophie Croizier*, Edson Mendes de Oliveira, Lukas K.J. Stadler, Soyoung Park, Youxin Kong, Matthew C. Banton, Panna Tandon, Audrey E. Hendricks, Julia M. Keogh, Susanna E. Riley, Sofia Papadia, Elana Henning, Rebecca Bounds, Elena G. Bochukova, Vanisha Mistry, Stephen O’Rahilly, Richard B. Simerly, INTERVAL, UK10K consortium, James E.N. Minchin, Inês Barroso, E. Yvonne Jones, Sebastien G. Bouret^, I. Sadaf Farooqi^. Cell. 2019 In Press.

  • Deep phenotyping in zebrafish reveals genetic and diet-induced adiposity changes that may inform disease risk. Minchin JEN^, Scahill CM, Staudt N, Busch-Nentwich EM, Rawls JF. Journal of Lipid Research. 2018 Aug;59(8):1536-1545. doi: 10.1194/jlr.D084525. PMID: 29794036

  • Adipose morphology and metabolic disease. Tandon P, Wafer R, Minchin JEN^. Journal of Experimental Biology. 2018 Mar 7;221(Pt Suppl 1). doi: 10.1242/jeb.164970. PMID: 29514883

  • Elucidating the role of plexin D1 in body fat distribution and susceptibility to metabolic disease using a zebrafish model system. Minchin JEN^, Rawls JF. Adipocyte. 2017 Oct 2;6(4):277-283. doi: 10.1080/21623945.2017.1356504. PMID: 28792859

  • The Role of Peroxisome Proliferator-Activated Receptor Gamma (PPARG) in Adipogenesis: Applying Knowledge from the Fish Aquaculture Industry to Biomedical Research. Wafer R, Tandon P, Minchin JEN^. Frontiers in Endocrinology. 2017 May 22;8:102. doi: 10.3389/fendo.2017.00102. PMID: 28588550

  • A classification system for zebrafish adipose tissues. Minchin JEN^, Rawls JF. Disease Models & Mechanisms. 2017 Jun 1;10(6):797-809. doi: 10.1242/dmm.025759. PMID: 28348140

  • In vivo imaging and quantification of regional adiposity in zebrafish. Minchin JE^, Rawls JF. Methods in Cell Biology. 2017 138:3-27. doi: 10.1016/bs.mcb.2016.11.010. PMID: 28129849

  • Plexin D1 determines body fat distribution by regulating the type V collagen microenvironment in visceral adipose tissue. Minchin JE, Dahlman I, Harvey CJ, Mejhert N, Singh MK, Epstein JA, Arner P, Torres-Vázquez J, Rawls JF. PNAS. 2015 Apr 7;112(14):4363-8. doi: 10.1073/pnas.1416412112. PMID: 25831505

  • Oesophageal and sternohyal muscle fibres are novel Pax3-dependent migratory somite derivatives essential for ingestion. Minchin JE, Williams VC, Hinits Y, Low S, Tandon P, Fan CM, Rawls JF, Hughes SM. Development. 2013 Jul;140(14):2972-84. doi: 10.1242/dev.090050. PMID: 23760954

  • Dwarfism and increased adiposity in the gh1 mutant zebrafish vizzini. McMenamin SK*, Minchin JE*, Gordon TN, Rawls JF, Parichy DM. Endocrinology. 2013 Apr;154(4):1476-87. doi: 10.1210/en.2012-1734. PMID: 23456361

  • In vivo analysis of white adipose tissue in zebrafish. Minchin JE, Rawls JF. Methods in Cell Biology. 2011 105:63-86. doi: 10.1016/B978-0-12-381320-6.00003-5. PMID: 21951526

The Minchin lab is part of the Centre for Cardiovascular Science at the University of Edinburgh